Iodin dusting-powder and process for making same



UNITED STATES PATENT OFFICE.

' NATHANYSULZBERGER, OF NEW YORK, N. Y. I

IODIN DUSTING-POWDEB AND PROCESS FOR MAKING SAME.

No Drawing.

To all whom it may concern:

Be it known that'I, NATHAN SULZBERGER, born in New York city, and a citizen of the United States, residing at New York city, in the county and State of New York, have invented newand useful Improvements in- Iodin Dusting-Powders and Processes for Making Same, of which the following is a" etc., have been disregarded by many practitioners, "particularly as disinfectants in .nose andear-work, where narrow passages present themselves and where free drainage is of especialimportance. I have found-that an iodin-dusting-pow- 'der possessing high disinfectant value andbeing free from this disadvantage and therefore particularly valuable in noseand earwork, can readily be prepared by spreading and distributing iodin in a very finely divided condition over a basea carrier,

, which is soluble in water. As such a carrier I have found boracic acid particularly valuable, since the same can be rendered into a very fine powder. which is readily soluble in water and easily impregnated with iodin in fine distribution. whereby such iodin can well exert its antiseptic properties, such iodin being finely distributed at the site of application concomitantly as th. boracic acid is dissolved in the aqueo s secretionsalways present in the tissues and mucous membranes. which are to be disinfected. The fact of being hygroscopic is of high advantage in this powder also for the reason, that by virtue of the same the secretions and bodies of a liquid nature tend to be drawn to the surface, osmosis started up, where they can more readily be treated and brought in contact with fresh amounts of the iodin powder. For this reason, the presence of an hygroscopic action in a dusting-powder is particularly desirable when the disinfectation and sterilization of tho narrowaural and nasal passages are des1red; The com Specificationpf Letters Patent. Patented Jan, 2'7, 1920,

Application filed October 14, 1915. Serial No. 55,756.

bination besides of two disinfectants of entirely different chemical nature (bora cic acid possessing also per se antiseptic action) is also .an advantage of such, iodin-dustingpowders, since it has been scientifically demonstrated that bacteriae, when treated with one and the same antiseptic, often become immune and resistant against the action of the same. I

In the following, I describe a method of preparing such iodin-dusting-powders, it being distinctly understood, however, that I am not limiting myself to the method here described or to the quality or quantity of materials employed in the below given illustrationz- To a solution of boracic acid in alcohol, was added an alcoholic solution containing iodin. After freeing from the alcohol, a brownish powder was obtained, which on being spread over a sheet of white paper readily discolored the same by virtue of its iodin content and which powder becomes whiter in color' on being exposed to the air by giving ofl more or less of its iodin content. When brought in contact with water, the boracic acid of the powder is readily dissolved out of the same, the water taking on a brown coloration. It is preferable when preparing the powder to employ a solution solvent, some of the iodin goes olf with such solvent. I prefer in many cases, especially, for noseand ear-work, to employ a dustingpowder containing about five per cent. of iodin. Other solvents or mixtures of same for the iodin than alcohol may be used, as

for instance. particularly also ether; it is not necessary that the boracic acid be in solution. It is advantageous to use an iodin solvent possessing a low boiling point. as smaller amounts of iodin will concomitantly be carried elf with the solvent. when evaporating the same out of the dusting-powder. In cases vacuum evaporation will be found of advantage.

By employing the iodin in form of a solution, the same will be more finely precipitatedupon tbe-boracic acid; in cases, however. a mechanical mixture of the iodin with the boracic acid may be found serviceable. Mixtures of iodin andboracic acid also with other substances possessing pharmaceutical value, shall be'conside'red as coming, under the scope of this invention.

It will accordingly. be seen that the antiseptic powders of the present invention, which are adapted for use as dusting powders, are made of boric acid in intimate association or combination with iodin .in amountssufiicient to exert the desired antiseptic properties so that the product possesses the antiseptic properties of both the iodin and the boracic acid, the iodin being distributed throughout the boracic acid and the impregnation or intimate association being preferably efl'ected as above described, 6. 9., by treating the boracic acid with a solution of iodin and evaporating the solvent.

I claim v v 1. An antiseptic powder adapted for use as a dusting powder and comprising boracic acid intimately combined with iodin in amount sufficient to exert antiseptic prop-' erties, the iodin being distributed throughout the boracic acid by deposition from solution. p

2. An antiseptic powder adapted for use as a dusting powder and comprising boracic acid impregnated with less than 10 per cent. of iodin? but with sufiicient iodin to exert antiseptic properties, tributed throughout the boracic acid by deposition from solution.

3. Process for making an antiseptic clustthe iodin being dising-powder which comprises the impregnation of boracic acid with iodin by. treating such boracic acid with a solution of iodin and evaporating the iodin solvent.

. NATHAN SULZBERGER. Witnesses:

. WM. C. BUETHE, J. A. GARRICK. 

